Early abnormal embryos of the rhesus monkey

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by , Washington
Rhesus monkey -- Embryology., Rhesus monkey -- Abnormali
Statement[by] George W. Corner and George W. Bartelmez.
SeriesIn Carnegie Institution of Washington. Contributions to embryology.
ContributionsBartelmez, George William, 1885-1967.
Classifications
LC ClassificationsQM601 .C3 vol. 35, no. 231
The Physical Object
Paginationv. 35 p. [1]-9.
ID Numbers
Open LibraryOL6195576M
LC Control Number56002857
OCLC/WorldCa1847598

Developmental Stages in the Rhesus Monkey (Macaca mulatta knowledge of the normal ontogenesis since only in that way can a reliable distinction be made between normal and abnormal or induced develop­ ment.

individual organs or their subunits the material used is classified according to the estimated age or the length of the embryos Format: Paperback. Much interest has been focused on this group of animals in general and on the rhesus monkey in particular because of its close phylo­ genetic relationship with man.

In some fields of research, however, such as embryology and microscopic anatomy, much less attention has been paid to nonhuman primates, probably because of the expense involved in. Totipotent cells in Early abnormal embryos of the rhesus monkey book embryos are progenitors of all stem cells and are capable of developing into a whole organism, including extraembryonic tissues such as placenta.

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Pluripotent cells in the inner cell mass (ICM) are the descendants of totipotent cells and can differentiate into any cell type of a body except extraembryonic by:   The Rhesus Monkey discusses the use of the rhesus monkey as a test subject in biomedical research.

This text provides information that is essential for research that involves the rhesus monkey, from conditioning a wild rhesus monkey to restoring Book Edition: 2. Preimplantation stages were collected from normal rhesus monkeys by flushing of the uterine lumen.

There was a high incidence of abnormal morulae and blastocysts (25%), as well as abnormal cells and cell death in otherwise normal blastocysts. Summary of Chimera Studies with Monkey Embryos and Embryonic Cells.

Rhesus monkey ESCs as well as isolated ICMs, blastomeres, or whole embryos were tested for their ability to incorporate into host embryos and generate chimeric offspring. Established ESCs and freshly isolated ICMs failed to produce chimeras when injected into host by: A co-culture system of rhesus monkey embryos and maternal immune cells was established.

Blastocysts obtained by in vitro fertilization were co-cultured with peripheral blood cells or decidual macrophages. Culture media were collected to assess by: 6. Because embryonic stem cells (ESCs) are derived from blastocyst stage embryos, they are used as a model for early embryo development.

Description Early abnormal embryos of the rhesus monkey EPUB

Methods: Rhesus monkey ESC lines (ORMES‐6 and ORMES‐7) were treated with 0, or % ethanol, % ethanol with estradiol, or % acetaldehyde with or without estradiol for 4 by: Laboratory and zoo housed non-human primates sometimes exhibit abnormal behaviors that are thought to reflect reduced well-being.

Previous research attempted to identify risk factors to aid in the prevention and treatment of these behaviors, and focused on demographic (e.g.

sex or age) and experience-related (e.g. single housing or nursery rearing) by: Morgan PM, Warikoo PK, Bavister, BD. In vitro maturation and fertilization of rhesus monkey oocytes [Abstract]. The primate ovary, final program and abstract book, Oregon Regional Primate Research Center, Beaverton, OR, May 16–17, Google ScholarCited by: Early abnormal embryos of the rhesus monkey: Embryology of the rhesus monkey (Macaca mulatta); collected papers from the Contributions to embryology, published by the Carnegie Institution of Washington.

The fate of the corpora lutea and the nature of the corpora aberrantia in the rhesus monkey.

Details Early abnormal embryos of the rhesus monkey FB2

Development of IVF, BB-SCNT, and MB-iSCNT embryos. Rhesus monkey ear fibroblast cells (Figure 1A) were fused with enucleated bovine oocytes (MB-iSCNT) using the same fusion parameters used for bovine fibroblasts (BB-SCNT).IVF bovine embryos were also cultured to control for the effect of the nuclear transfer (NT) by: This study provides some insight into the cleavage patterns that do result in blastocyst formation in rhesus embryos and to the fate of embryos with abnormal early cleavage patterns.

The temporal development for the blastocysts in this study corresponded to the timelines previously reported for in vivo development previously reported by Goodeaux and coworkers Cited by: Enders AC, Schlafke S () Differentiation of the blastocyst of the rhesus monkey.

Am J Anat l, 1–21 CrossRef Google Scholar Hertig AT, Rock J, Adams EC, Mulligan W () On the preimplantation stages of the human ovum: A description of four normal and four abnormal specimens ranging from the second to the fifth day of by: The POU (Pit-Oct-Unc)-domain transcription factor, Oct-4, has become a useful marker of pluripotency in the mouse.

It is found exclusively in mouse preimplantation-stage embryos after embryonic genome activation and is a characteristic of mouse embryonic stem (ES) cells, and its absence in knockout.

Introduction. X chromosome inactivation is believed to be an essential mechanism regulating the dosage compensation of X-linked genes in eutherian mammals so that females with two X chromosomes do not overexpress X-linked genes compared to males ().XCI is initiated during early mouse preimplantation embryo development, where the paternally inherited X chromosome is silenced in early cleaving Cited by: Cloning of Rhesus Monkey The journal “Nature” published an article by a group of American scientists on the cloning of rhesus monkeys.

American scientists from the University of Oregon Health and Sciences have cloned monkeys and used their embryos to obtain embryonic stem cells.

Effects of Early Rearing Environment on Immune-Responses of Infant Rhesus Monkeys. Author links open overlay panel Lubach G.R.

Coe C.L. Ershler W.B. Our observation is consistent with results obtained in rhesus monkey oocytes, where assessment of fertilization, as evidenced by the presence of pronuclei, was performed 10–12 h after ICSI.

Although the two embryos developed to the 10‐cell stage, they arrested and failed to reach the blastocyst : Hideaki Watanabe, Takuya Matsumoto, Moeka Nishi, Ken Takeshi Kusakabe, Takeshi Kuraishi, Shosaku Hat. Fertilization and embryo development to blastocysts by intracytoplasmic sperm injection in the rhesus monkey Article (PDF Available) in Human Reproduction 13(12) January with Reads.

Because embryonic stem cells (ESCs) are derived from blastocyst stage embryos, they are used as a model for early embryo development. Methods Rhesus monkey ESC lines (ORMES-6 and -7) were treated with 0, %, %, or % ethanol, % ethanol with estradiol or % acetaldehyde with or without estradiol for 4 by:   Early abnormal embryos of the rhesus monkey by George Washington Corner 1 edition - first published in   Rhesus macaque and human preimplantation embryos display similar rates of chromosomal abnormalities.

The aim of this study was to determine whether embryos developing from MI oocytes that mature post-retrieval display more chromosomal anomalies than those embryos that are generated from oocytes that are at MII at the time of by:   The researchers implanted the chimeric embryos into five female rhesus monkeys, all of which became pregnant.

Tests on the foetuses confirmed that all of Author: Ian Sample. surrogate mothers, resulted in pregnancies to term [11, 13]; though one cloned monkey offspring has been achieved by embryonic cell nuclear transfer [15].

15 In order to explore which factors could actually affect the early or late development of these reconstructed embryos, we focused in this study on epigenetic reprogramming of the donor cells. In the rhesus monkey, the participation of the sperm head in ICSI-induced oocyte activation has been documented (Meng and Wolf, ) and, recently, the first ICSI monkey was born following transfer of an 8-cell stage embryo (Hewitson et al., ).Cited by:   They removed the chromosomes from unfertilized monkey eggs and replaced them with nuclei from the skin cells of an adult rhesus monkey (Macaca mulatta).

A total of oocytes yielded 21 Cited by: 1. Since abnormal and/or anovulatory menstrual cycles are characteristic of rhesus monkeys >18 years of age (Gilardi et al., ; Shideler et al., ; present study), and age-related changes in endocrine function and follicular populations were evident in the present study, results were unlikely to have been confounded by homogeneity in the Cited by: Scientists have produced the world's first chimeric monkeys, developed from stem cells harvested from separate embryos.

They contain genetic material from as many as six genomes. The infant rhesus. Until now, no primate animals have been successfully cloned to birth with somatic cell nuclear transfer (SCNT) procedures, and little is known about the molecular events that occurred in the reconstructed embryos during preimplantation development.

In many SCNT cases, epigenetic reprogramming of the donor nuclei after transfer into enucleated oocytes was hypothesized to be crucial to the Cited by:.

Rhesus monkey, (Macaca mulatta), sand-coloured primate native to forests but also found coexisting with humans in northern India, Nepal, eastern and southern China, and northern Southeast Asia.

The rhesus monkey is the best-known species of macaque and measures about 47–64 cm .The embryos collected from superovulated rhesus monkeys (morulae and early blastocysts) would be expected to have high viability, which would benefit not only studies on age-related infertility but also production of better quality embryonic stem cells.Monkey pronuclear-stage zygotes and cleaving embryos up to the 8-cell stage showed no detectable Oct Nuclear staining for Oct-4 first became obvious at the cell stage, and a strong signal was observed in morula and compact morula stages.

Both ICM and trophectodermal cell nuclei of monkey early blastocysts were positive for OctCited by: